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SYGL-1 and LST-1 link niche signaling to PUF RNA repression for stem cell maintenance in Caenorhabditis elegans

Central questions in regenerative biology include how stem cells are maintained and how they transition from self-renewal to differentiation. Germline stem cells (GSCs) in Caeno-rhabditis elegans provide a tractable in vivo model to address these questions. In this system, Notch signaling and PUF RN...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Shin, Heaji, Haupt, Kimberly A., Kershner, Aaron M., Kroll-Conner, Peggy, Wickens, Marvin, Kimble, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741267/
https://ncbi.nlm.nih.gov/pubmed/29232700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007121
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