The molecular basis of LST-1 self-renewal activity and its control of stem cell pool size

PUF RNA-binding proteins have diverse roles in animal development, with a broadly conserved role in stem cells. Two paradigmatic PUF proteins, FBF-1 and FBF-2, promote both self-renewal and differentiation in the C. elegans germline. The LST-1 protein is a pivotal regulator of self-renewal and is on...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Development
Asıl Yazarlar: Haupt, Kimberly A., Enright, Amy L., Ferdous, Ahlan S., Kershner, Aaron M., Shin, Heaji, Wickens, Marvin, Kimble, Judith
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists Ltd 2019
Konular:
Stem Cells and Regeneration
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826033/
https://ncbi.nlm.nih.gov/pubmed/31515205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.181644
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