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Inhibiting SUMO1-mediated SUMOylation induces autophagy-mediated cancer cell death and reduces tumour cell invasion via RAC1

Post-translational modifications directly control protein activity and, thus, they represent an important means to regulate the responses of cells to different stimuli. Protein SUMOylation has recently been recognised as one such modification, and it has been associated with various diseases, includ...

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Bibliografiske detaljer
Udgivet i:J Cell Sci
Main Authors: Lorente, Mar, García-Casas, Ana, Salvador, Nélida, Martínez-López, Angélica, Gabicagogeascoa, Estibaliz, Velasco, Guillermo, López-Palomar, Lucía, Castillo-Lluva, Sonia
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826015/
https://ncbi.nlm.nih.gov/pubmed/31578236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.234120
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