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Protein sumoylation with SUMO1 promoted by Pin1 in glioma stem cells augments glioblastoma malignancy

BACKGROUND: The tumorigenic potential of glioma stem cells (GSCs) is associated with multiple reversible molecular alternations, but the role of posttranslational protein sumoylation in GSCs has not been elucidated. The development of GSC-targeting drugs relies on the discovery of GSC-preferential m...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Zhang, Aili, Tao, Weiwei, Zhai, Kui, Fang, Xiaoguang, Huang, Zhi, Yu, Jennifer S, Sloan, Andrew E, Rich, Jeremy N, Zhou, Wenchao, Bao, Shideng
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746948/
https://ncbi.nlm.nih.gov/pubmed/32592588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa150
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