Protein sumoylation with SUMO1 promoted by Pin1 in glioma stem cells augments glioblastoma malignancy

BACKGROUND: The tumorigenic potential of glioma stem cells (GSCs) is associated with multiple reversible molecular alternations, but the role of posttranslational protein sumoylation in GSCs has not been elucidated. The development of GSC-targeting drugs relies on the discovery of GSC-preferential m...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Neuro Oncol
Hlavní autoři: Zhang, Aili, Tao, Weiwei, Zhai, Kui, Fang, Xiaoguang, Huang, Zhi, Yu, Jennifer S, Sloan, Andrew E, Rich, Jeremy N, Zhou, Wenchao, Bao, Shideng
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746948/
https://ncbi.nlm.nih.gov/pubmed/32592588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa150
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky