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Inhibiting SUMO1-mediated SUMOylation induces autophagy-mediated cancer cell death and reduces tumour cell invasion via RAC1

Post-translational modifications directly control protein activity and, thus, they represent an important means to regulate the responses of cells to different stimuli. Protein SUMOylation has recently been recognised as one such modification, and it has been associated with various diseases, includ...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Sci
Hauptverfasser: Lorente, Mar, García-Casas, Ana, Salvador, Nélida, Martínez-López, Angélica, Gabicagogeascoa, Estibaliz, Velasco, Guillermo, López-Palomar, Lucía, Castillo-Lluva, Sonia
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826015/
https://ncbi.nlm.nih.gov/pubmed/31578236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.234120
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