Genetic Characterization and Prognostic Relevance of Acquired Uniparental Disomies in Cytogenetically Normal Acute Myeloid Leukemia

PURPOSE: Uniparental disomy UPD is a way cancer cells duplicate a mutated gene causing loss of heterozygosity (LOH). Patients with cytogenetically normal acute myeloid leukemia (CN-AML) do not have microscopically detectable chromosome abnormalities, but can harbor UPDs. We examined the prognostic s...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Clin Cancer Res
Huvudupphovsmän: Walker, Christopher J., Kohlschmidt, Jessica, Eisfeld, Ann-Kathrin, Mrózek, Krzysztof, Liyanarachchi, Sandya, Song, Chi, Nicolet, Deedra, Blachly, James S., Bill, Marius, Papaioannou, Dimitrios, Oakes, Christopher C., Giacopelli, Brain, Genutis, Luke K., Maharry, Sophia E., Orwick, Shelley, Archer, Kellie J., Powell, Bayard L., Kolitz, Jonathan E., Uy, Geoffrey L., Wang, Eunice S., Carroll, Andrew J., Stone, Richard M., Byrd, John C., de la Chapelle, Albert, Bloomfield, Clara D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825549/
https://ncbi.nlm.nih.gov/pubmed/31375516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-0725
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk