Glutaminolysis‐related genes determine sensitivity to xCT‐targeted therapy in head and neck squamous cell carcinoma

Targeting the function of membrane transporters in cancer stemlike cells is a potential new therapeutic approach. Cystine‐glutamate antiporter xCT expressed in CD44 variant (CD44v)‐expressing cancer cells contributes to the resistance to oxidative stress as well as cancer therapy through promoting g...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Sci
Main Authors: Okazaki, Shogo, Umene, Kiyoko, Yamasaki, Juntaro, Suina, Kentaro, Otsuki, Yuji, Yoshikawa, Momoko, Minami, Yushi, Masuko, Takashi, Kawaguchi, Sho, Nakayama, Hideki, Banno, Kouji, Aoki, Daisuke, Saya, Hideyuki, Nagano, Osamu
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825010/
https://ncbi.nlm.nih.gov/pubmed/31444923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14182
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