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Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B‐containing N‐methyl‐d‐aspartate–sensitive glutamate receptor signaling

Autocrine and paracrine factors, including glutamate and epidermal growth factor (EGF), are potent inducers of brain tumor cell invasion, a pathological hallmark of malignant gliomas. System xc(–) consists of xCT and CD98hc subunits and functions as a plasma membrane antiporter for the uptake of ext...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Sci
Prif Awduron: Suina, Kentaro, Tsuchihashi, Kenji, Yamasaki, Juntaro, Kamenori, Shohei, Shintani, Subaru, Hirata, Yuki, Okazaki, Shogo, Sampetrean, Oltea, Baba, Eishi, Akashi, Koichi, Mitsuishi, Yoichiro, Takahashi, Fumiyuki, Takahashi, Kazuhisa, Saya, Hideyuki, Nagano, Osamu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272110/
https://ncbi.nlm.nih.gov/pubmed/30298963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13826
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