Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B‐containing N‐methyl‐d‐aspartate–sensitive glutamate receptor signaling

Autocrine and paracrine factors, including glutamate and epidermal growth factor (EGF), are potent inducers of brain tumor cell invasion, a pathological hallmark of malignant gliomas. System xc(–) consists of xCT and CD98hc subunits and functions as a plasma membrane antiporter for the uptake of ext...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Suina, Kentaro, Tsuchihashi, Kenji, Yamasaki, Juntaro, Kamenori, Shohei, Shintani, Subaru, Hirata, Yuki, Okazaki, Shogo, Sampetrean, Oltea, Baba, Eishi, Akashi, Koichi, Mitsuishi, Yoichiro, Takahashi, Fumiyuki, Takahashi, Kazuhisa, Saya, Hideyuki, Nagano, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272110/
https://ncbi.nlm.nih.gov/pubmed/30298963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13826
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