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Sulfasalazine could modulate the CD44v9‐xCT system and enhance cisplatin‐induced cytotoxic effects in metastatic bladder cancer

The prognostic role of CD44v9, a variant isoform of CD44 and a new cell surface marker of cancer stem cells, remains unclear in bladder cancer (BC) patients. Furthermore, limited information is available on the functional role of sulfasalazine (SSZ), which could modulate the CD44v9‐xCT system in ord...

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Vydáno v:Cancer Sci
Hlavní autoři: Ogihara, Koichiro, Kikuchi, Eiji, Okazaki, Shogo, Hagiwara, Masayuki, Takeda, Toshikazu, Matsumoto, Kazuhiro, Kosaka, Takeo, Mikami, Shuji, Saya, Hideyuki, Oya, Mototsugu
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447829/
https://ncbi.nlm.nih.gov/pubmed/30719824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13960
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