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Targeting centrosome amplification, an Achilles' heel of cancer
Due to cell-cycle dysregulation, many cancer cells contain more than the normal compliment of centrosomes, a state referred to as centrosome amplification (CA). CA can drive oncogenic phenotypes and indeed can cause cancer in flies and mammals. However, cells have to actively manage CA, often by cen...
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| 出版年: | Biochem Soc Trans |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Portland Press Ltd.
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6824836/ https://ncbi.nlm.nih.gov/pubmed/31506331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20190034 |
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