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Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy
The mitogen-activated protein kinases (MAPK) pathway, often known as the RAS-RAF-MEK-ERK signal cascade, functions to transmit upstream signals to its downstream effectors to regulate physiological process such as cell proliferation, differentiation, survival and death. As the most frequently mutate...
Zapisane w:
| Wydane w: | Acta Pharm Sin B |
|---|---|
| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Elsevier
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6089851/ https://ncbi.nlm.nih.gov/pubmed/30109180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2018.01.008 |
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