Role of β-glucosidase 2 in aberrant glycosphingolipid metabolism: model of glucocerebrosidase deficiency in zebrafish

β-glucosidases [GBA1 (glucocerebrosidase) and GBA2] are ubiquitous essential enzymes. Lysosomal GBA1 and cytosol-facing GBA2 degrade glucosylceramide (GlcCer); GBA1 deficiency causes Gaucher disease, a lysosomal storage disorder characterized by lysosomal accumulation of GlcCer, which is partly conv...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Lipid Res
Main Authors: Lelieveld, Lindsey T., Mirzaian, Mina, Kuo, Chi-Lin, Artola, Marta, Ferraz, Maria J., Peter, Remco E. A., Akiyama, Hisako, Greimel, Peter, van den Berg, Richard J. B. H. N., Overkleeft, Herman S., Boot, Rolf G., Meijer, Annemarie H., Aerts, Johannes M. F. G.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824494/
https://ncbi.nlm.nih.gov/pubmed/31562193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000154
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker