Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates

Translation of drug candidates into clinical settings requires demonstration of preclinical efficacy and formal toxicology analysis for filling an Investigational New Drug (IND) application with the US Food & Drug Administration (FDA). Here, we investigate the membrane-associated glucose respons...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Pharmacogenomics J
Main Authors: Staquicini, Daniela I., D’Angelo, Sara, Ferrara, Fortunato, Karjalainen, Katja, Sharma, Geetanjali, Smith, Tracey L., Tarleton, Christy A., Jaalouk, Diana E., Kuniyasu, Akihiko, Baze, Wallace B., Chaffee, Beth K., Hanley, Patrick W., Barnhart, Kirstin F., Koivunen, Erkki, Marchiò, Serena, Sidman, Richard L., Cortes, Jorge E., Kantarjian, Hagop M., Arap, Wadih, Pasqualini, Renata
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824482/
https://ncbi.nlm.nih.gov/pubmed/29205207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2017.46
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares