Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates

Translation of drug candidates into clinical settings requires demonstration of preclinical efficacy and formal toxicology analysis for filling an Investigational New Drug (IND) application with the US Food & Drug Administration (FDA). Here, we investigate the membrane-associated glucose respons...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Pharmacogenomics J
Main Authors: Staquicini, Daniela I., D’Angelo, Sara, Ferrara, Fortunato, Karjalainen, Katja, Sharma, Geetanjali, Smith, Tracey L., Tarleton, Christy A., Jaalouk, Diana E., Kuniyasu, Akihiko, Baze, Wallace B., Chaffee, Beth K., Hanley, Patrick W., Barnhart, Kirstin F., Koivunen, Erkki, Marchiò, Serena, Sidman, Richard L., Cortes, Jorge E., Kantarjian, Hagop M., Arap, Wadih, Pasqualini, Renata
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824482/
https://ncbi.nlm.nih.gov/pubmed/29205207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2017.46
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados