Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression

Tissue engineering may address organ shortages currently limiting clinical transplantation. Off-the-shelf engineered vascularized organs will likely use allogeneic endothelial cells (ECs) to construct microvessels required for graft perfusion. Vasculogenic ECs can be differentiated from committed pr...

詳細記述

保存先:
書誌詳細
出版年:JCI Insight
主要な著者: Merola, Jonathan, Reschke, Melanie, Pierce, Richard W., Qin, Lingfeng, Spindler, Susann, Baltazar, Tania, Manes, Thomas D., Lopez-Giraldez, Francesc, Li, Guangxin, Bracaglia, Laura G., Xie, Catherine, Kirkiles-Smith, Nancy, Saltzman, W. Mark, Tietjen, Gregory T., Tellides, George, Pober, Jordan S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2019
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824302/
https://ncbi.nlm.nih.gov/pubmed/31527312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129739
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