DHX15 is up-regulated in castration-resistant prostate cancer and required for androgen receptor sensitivity to low DHT concentrations

BACKGROUND: DHX15 is a member of the DEAH-box (DHX) RNA helicase family. Our previous study identified it as an AR coactivator which contributes to prostate cancer progression. METHODS: We investigated DHX15 expression in castration resistant prostate cancer specimens and the influence of DHX15 on t...

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Pubblicato in:Prostate
Autori principali: Xu, Yadong, Song, Qiong, Pascal, Laura E., Zhong, Mingming, Zhou, Yibin, Zhou, Jianhua, Deng, Fang‐Ming, Huang, Jiaoti, Wang, Zhou
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823643/
https://ncbi.nlm.nih.gov/pubmed/30714180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23773
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