Regulation and targeting of androgen receptor nuclear localization in castration-resistant prostate cancer

Nuclear localization of the androgen receptor (AR) is necessary for its activation as a transcription factor. Defining the mechanisms regulating AR nuclear localization in androgen-sensitive cells and how these mechanisms are dysregulated in castration-resistant prostate cancer (CRPC) cells is funda...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Lv, Shidong, Song, Qiong, Chen, Guang, Cheng, Erdong, Chen, Wei, Cole, Ryan, Wu, Zeyu, Pascal, Laura E., Wang, Ke, Wipf, Peter, Nelson, Joel B., Wei, Qiang, Huang, Wenhua, Wang, Zhou
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2021
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880411/
https://ncbi.nlm.nih.gov/pubmed/33332287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI141335
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