A gain of function mutation in DHT synthesis in castration-resistant prostate cancer

Growth of prostate cancer cells is dependent upon androgen stimulation of the androgen receptor (AR). Dihydrotestosterone (DHT), the most potent androgen, is usually synthesized in the prostate from testosterone secreted by the testis. Following chemical or surgical castration, prostate cancers usua...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Chang, Kai-Hsiung, Li, Rui, Kuri, Barbara, Lotan, Yair, Roehrborn, Claus G., Liu, Jiayan, Vessella, Robert, Nelson, Peter, Kapur, Payal, Guo, Xiaofeng, Mirzaei, Hamid, Auchus, Richard J., Sharifi, Nima
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931012/
https://ncbi.nlm.nih.gov/pubmed/23993097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.07.029
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker