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“Getting from here to there” - Mechanisms and Limitations to the Activation of the Androgen Receptor in Castration-Resistant Prostate Cancer

Despite the clinical regression that typifies the initial response of advanced prostate cancer to gonadal testosterone depletion, tumors eventually progress. However, evidence supports the concept that signaling via the androgen receptor (AR) is important in progression to castration-resistant prost...

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Detalhes bibliográficos
Publicado no:J Investig Med
Main Authors: Sharifi, Nima, McPhaul, Michael J., Auchus, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589138/
https://ncbi.nlm.nih.gov/pubmed/21030877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.231/JIM.0b013e3181ff6bb8
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