Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Inhibits Proximal TCR Signaling by Targeting ZAP-70

The long cytoplasmic tail (CT) isoforms of carcinoembryonic Ag-related cell adhesion molecule 1 (CEACAM1) are expressed on activated human T cells and possess two ITIM motifs in the CT. These isoforms of CEACAM1 are inhibitory for T cell responses initiated by the TCR/CD3 complex with the inhibition...

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Bibliografiska uppgifter
I publikationen:J Immunol
Huvudupphovsmän: Chen, Zhangguo, Chen, Lanfen, Qiao, Shuo-Wang, Nagaishi, Takashi, Blumberg, Richard S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822693/
https://ncbi.nlm.nih.gov/pubmed/18424730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.180.9.6085
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