Regulation of hepatic fibrosis by Carcinoembryonic Antigen-related Cell Adhesion Molecule 1

OBJECTIVE: NAFLD is a complex disease marked by cellular abnormalities leading to NASH. NAFLD patients manifest low hepatic levels of CEACAM1, a promoter of insulin clearance. Consistently, Cc1(−/−) null mice displayed spontaneous hyperinsulinemia/insulin resistance and steatohepatitis. Liver-specif...

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Bibliographic Details
Published in:Metabolism
Main Authors: Helal, Raghd Abu, Russo, Lucia, Ghadieh, Hilda E., Muturi, Harrison T., Asalla, Suman, Lee, Abraham D., Gatto-Weis, Cara, Najjar, Sonia M.
Format: Artigo
Language:Inglês
Published: 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286970/
https://ncbi.nlm.nih.gov/pubmed/34058224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2021.154801
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