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Regulation of hepatic fibrosis by Carcinoembryonic Antigen-related Cell Adhesion Molecule 1
OBJECTIVE: NAFLD is a complex disease marked by cellular abnormalities leading to NASH. NAFLD patients manifest low hepatic levels of CEACAM1, a promoter of insulin clearance. Consistently, Cc1(−/−) null mice displayed spontaneous hyperinsulinemia/insulin resistance and steatohepatitis. Liver-specif...
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| Pubblicato in: | Metabolism |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8286970/ https://ncbi.nlm.nih.gov/pubmed/34058224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2021.154801 |
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