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Pharmacophore and docking-based sequential virtual screening for the identification of novel Sigma 1 receptor ligands
Sigma 1 receptor (σ1), a small transmembrane protein expressed in most human cells participates in modulating the function of other membrane proteins such as G protein coupled receptors and ion channels. Several ligands targeting this receptor are currently in clinical trials for the treatment of Al...
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| Udgivet i: | Bioinformation |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Biomedical Informatics
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6822515/ https://ncbi.nlm.nih.gov/pubmed/31719769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630015586 |
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