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Pharmacophore and docking-based sequential virtual screening for the identification of novel Sigma 1 receptor ligands

Sigma 1 receptor (σ1), a small transmembrane protein expressed in most human cells participates in modulating the function of other membrane proteins such as G protein coupled receptors and ion channels. Several ligands targeting this receptor are currently in clinical trials for the treatment of Al...

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Vydáno v:Bioinformation
Hlavní autoři: Alamri, Mubarak A, Alamri, Mohammed A
Médium: Artigo
Jazyk:Inglês
Vydáno: Biomedical Informatics 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822515/
https://ncbi.nlm.nih.gov/pubmed/31719769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630015586
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