SLX4IP acts with SLX4 and XPF–ERCC1 to promote interstrand crosslink repair

Interstrand crosslinks (ICLs) are highly toxic DNA lesions that are repaired via a complex process requiring the coordination of several DNA repair pathways. Defects in ICL repair result in Fanconi anemia, which is characterized by bone marrow failure, developmental abnormalities, and a high inciden...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Zhang, Huimin, Chen, Zhen, Ye, Yin, Ye, Zu, Cao, Dan, Xiong, Yun, Srivastava, Mrinal, Feng, Xu, Tang, Mengfan, Wang, Chao, Tainer, John A, Chen, Junjie
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821277/
https://ncbi.nlm.nih.gov/pubmed/31495888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz769
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