XPF-ERCC1 acts in unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4

DNA interstrand crosslinks (ICLs), highly toxic lesions that covalently link the Watson and Crick strands of the double helix, are repaired by a complex, replication-coupled pathway in higher eukaryotes. The earliest DNA processing event in ICL repair is the incision of parental DNA on either side o...

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Bibliografiska uppgifter
I publikationen:Mol Cell
Huvudupphovsmän: Douwel, Daisy Klein, Boonen, Rick A.C.M., Long, David T., Szypowska, Anna A., Räschle, Markus, Walter, Johannes C., Knipscheer, Puck
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067070/
https://ncbi.nlm.nih.gov/pubmed/24726325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.03.015
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