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A high-throughput drug combination screen of targeted small molecule inhibitors in cancer cell lines

While there is a high interest in drug combinations in cancer therapy, openly accessible datasets for drug combination responses are sparse. Here we present a dataset comprising 171 pairwise combinations of 19 individual drugs targeting signal transduction mechanisms across eight cancer cell lines,...

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Dettagli Bibliografici
Pubblicato in:Sci Data
Autori principali: Flobak, Åsmund, Niederdorfer, Barbara, Nakstad, Vu To, Thommesen, Liv, Klinkenberg, Geir, Lægreid, Astrid
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820772/
https://ncbi.nlm.nih.gov/pubmed/31664030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41597-019-0255-7
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