Architectural Modification of Conformal PEG-Bottlebrush Coatings Minimizes Anti-PEG Antigenicity While Preserving Stealth Properties

Poly(ethylene glycol) (PEG), a linear polymer known for its “stealth” properties, is commonly used to passivate the surface of biomedical implants and devices, and is conjugated to biologic drugs to improve their pharmacokinetics. However, its antigenicity is a growing concern. Here, we investigated...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Adv Healthc Mater
Autors principals: Joh, Daniel Y., Zimmers, Zackary, Avlani, Manav, Heggestad, Jacob T., Aydin, Hakan B., Ganson, Nancy, Kumar, Shourya, Fontes, Cassio, Achar, Rohan K., Hershfield, Michael S., Hucknall, Angus M., Chilkoti, Ashutosh
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819148/
https://ncbi.nlm.nih.gov/pubmed/30908902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201801177
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars