AAV8-vectored suprachoroidal gene transfer produces widespread ocular transgene expression

There has been great progress in ocular gene therapy, but delivery of viral vectors to the retinal pigmented epithelium (RPE) and retina can be challenging. Subretinal injection, the preferred route of delivery for most applications, requires a surgical procedure that has risks. Herein we report a n...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Ding, Kun, Shen, Jikui, Hafiz, Zibran, Hackett, Sean F., Silva, Raquel Lima e, Khan, Mahmood, Lorenc, Valeria E., Chen, Daiqin, Chadha, Rishi, Zhang, Minie, Van Everen, Sherri, Buss, Nicholas, Fiscella, Michele, Danos, Olivier, Campochiaro, Peter A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819121/
https://ncbi.nlm.nih.gov/pubmed/31408444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI129085
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky