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AAV8-antiVEGFfab Ocular Gene Transfer for Neovascular Age-Related Macular Degeneration

Sustained suppression of VEGF is needed in many patients with neovascular age-related macular degeneration (NVAMD), and gene transfer of a VEGF-neutralizing protein is a promising approach to achieve it. Initial clinical trials testing this approach have shown encouraging signals, but evidence of ro...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Liu, Yuanyuan, Fortmann, Seth D., Shen, Jikui, Wielechowski, Erik, Tretiakova, Anna, Yoo, Stephen, Kozarsky, Karen, Wang, Jiangxia, Wilson, James M., Campochiaro, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835120/
https://ncbi.nlm.nih.gov/pubmed/29292162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.12.002
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