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The HIF-1 Antagonist Acriflavine; Visualization in Retina and Suppression of Ocular Neovascularization
Acriflavine, a fluorescent drug previously used for bacterial and trypanosomal infections, reduces hypoxia-inducible factor-1 (HIF-1) and HIF-2 transcriptional activity. In mice with oxygen-induced ischemic retinopathy, intraocular or intraperitoneal injections of acriflavine caused dose-dependent s...
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| Publicado no: | J Mol Med (Berl) |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5357443/ https://ncbi.nlm.nih.gov/pubmed/28004126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-016-1498-9 |
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