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Hepatocyte growth factor is upregulated in ischemic retina and contributes to retinal vascular leakage and neovascularization

In patients with macular edema due to ischemic retinopathy, aqueous levels of hepatocyte growth factor (HGF) correlate with edema severity. We tested whether HGF expression and activity in mice with oxygen‐induced ischemic retinopathy supports a role in macular edema. In ischemic retina, HGF was inc...

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Detalhes bibliográficos
Publicado no:FASEB Bioadv
Main Authors: Lorenc, Valeria E., Lima e Silva, Raquel, Hackett, Sean F., Fortmann, Seth D., Liu, Yuanyuan, Campochiaro, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7133726/
https://ncbi.nlm.nih.gov/pubmed/32259049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2019-00074
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