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Chemotherapy-induced cellular senescence suppresses progression of Notch-driven T-ALL

T cell acute lymphoblastic leukemia (T-ALL) is a serious hematologic malignancy that occurs in children and young adults. Current therapies include intensive chemotherapy and ionizing radiation that preferentially kill malignant cells. Unfortunately, they are frequently accompanied by unintended neg...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Zhang, Ying, Gundelach, Justin, Lindquist, Lonnie D., Baker, Darren J., van Deursen, Jan, Bram, Richard J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818774/
https://ncbi.nlm.nih.gov/pubmed/31661505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224172
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