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Cellular senescence in aging and age-related disease: from mechanisms to therapy

Cellular senescence, a process that imposes permanent proliferative arrest on cells in response to various stressors, has emerged as a potentially important contributor to aging and age-related disease, and it is an attractive target for therapeutic exploitation. A wealth of information about senesc...

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Détails bibliographiques
Publié dans:Nat Med
Auteurs principaux: Childs, Bennett G, Durik, Matej, Baker, Darren J, van Deursen, Jan M
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748967/
https://ncbi.nlm.nih.gov/pubmed/26646499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4000
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