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Senescent cells: an emerging target for diseases of ageing

Chronological age represents the single greatest risk factor for human disease. One plausible explanation for this correlation is that mechanisms that drive ageing might also promote age-related diseases. Cellular senescence, which is a permanent state of cell cycle arrest induced by cellular stress...

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Detalles Bibliográficos
Publicado en:Nat Rev Drug Discov
Main Authors: Childs, Bennett G., Gluscevic, Martina, Baker, Darren J., Laberge, Remi-Martin, Marquess, Dan, Dananberg, Jamie, van Deursen, Jan M.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942225/
https://ncbi.nlm.nih.gov/pubmed/28729727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2017.116
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