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Senescence and apoptosis: dueling or complementary cell fates?

In response to a variety of stresses, mammalian cells undergo a persistent proliferative arrest known as cellular senescence. Many senescence-inducing stressors are potentially oncogenic, strengthening the notion that senescence evolved alongside apoptosis to suppress tumorigenesis. In contrast to a...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Childs, Bennett G, Baker, Darren J, Kirkland, James L, Campisi, Judith, van Deursen, Jan M
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253488/
https://ncbi.nlm.nih.gov/pubmed/25312810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439245
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