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Pak2 kinase promotes cellular senescence and organismal aging
Cellular senescence defines an irreversible cell growth arrest state linked to loss of tissue function and aging in mammals. This transition from proliferation to senescence is typically characterized by increased expression of the cell-cycle inhibitor p16(INK4a) and formation of senescence-associat...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6613284/ https://ncbi.nlm.nih.gov/pubmed/31209047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903847116 |
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