The systemic activin response to pancreatic cancer: implications for effective cancer cachexia therapy

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a particularly lethal malignancy partly due to frequent, severe cachexia. Serum activin correlates with cachexia and mortality, while exogenous activin causes cachexia in mice. METHODS: Isoform‐specific activin expression and activities were que...

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Vydáno v:J Cachexia Sarcopenia Muscle
Hlavní autoři: Zhong, Xiaoling, Pons, Marianne, Poirier, Christophe, Jiang, Yanlin, Liu, Jianguo, Sandusky, George E., Shahda, Safi, Nakeeb, Attila, Schmidt, C. Max, House, Michael G., Ceppa, Eugene P., Zyromski, Nicholas J., Liu, Yunlong, Jiang, Guanglong, Couch, Marion E., Koniaris, Leonidas G., Zimmers, Teresa A.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818463/
https://ncbi.nlm.nih.gov/pubmed/31286691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12461
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