The systemic activin response to pancreatic cancer: implications for effective cancer cachexia therapy

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a particularly lethal malignancy partly due to frequent, severe cachexia. Serum activin correlates with cachexia and mortality, while exogenous activin causes cachexia in mice. METHODS: Isoform‐specific activin expression and activities were que...

詳細記述

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書誌詳細
出版年:J Cachexia Sarcopenia Muscle
主要な著者: Zhong, Xiaoling, Pons, Marianne, Poirier, Christophe, Jiang, Yanlin, Liu, Jianguo, Sandusky, George E., Shahda, Safi, Nakeeb, Attila, Schmidt, C. Max, House, Michael G., Ceppa, Eugene P., Zyromski, Nicholas J., Liu, Yunlong, Jiang, Guanglong, Couch, Marion E., Koniaris, Leonidas G., Zimmers, Teresa A.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2019
主題:
Original Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818463/
https://ncbi.nlm.nih.gov/pubmed/31286691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12461
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