The systemic activin response to pancreatic cancer: implications for effective cancer cachexia therapy

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a particularly lethal malignancy partly due to frequent, severe cachexia. Serum activin correlates with cachexia and mortality, while exogenous activin causes cachexia in mice. METHODS: Isoform‐specific activin expression and activities were que...

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Detalhes bibliográficos
Publicado no:J Cachexia Sarcopenia Muscle
Main Authors: Zhong, Xiaoling, Pons, Marianne, Poirier, Christophe, Jiang, Yanlin, Liu, Jianguo, Sandusky, George E., Shahda, Safi, Nakeeb, Attila, Schmidt, C. Max, House, Michael G., Ceppa, Eugene P., Zyromski, Nicholas J., Liu, Yunlong, Jiang, Guanglong, Couch, Marion E., Koniaris, Leonidas G., Zimmers, Teresa A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818463/
https://ncbi.nlm.nih.gov/pubmed/31286691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12461
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