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Biochemical and Structural Insights Concerning Triclosan Resistance in a Novel YX(7)K Type Enoyl-Acyl Carrier Protein Reductase from Soil Metagenome
Enoyl-acyl carrier protein reductase (ENR) catalyzes the last reduction step in the bacterial type II fatty acid biosynthesis cycle. ENRs include FabI, FabL, FabL2, FabK, and FabV. Previously, we reported a unique triclosan (TCL) resistant ENR homolog that was predominant in obligate intracellular p...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6817880/ https://ncbi.nlm.nih.gov/pubmed/31659200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51895-2 |
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