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Critical Structural Defects Explain Filamin A Mutations Causing Mitral Valve Dysplasia
Mitral valve diseases affect ∼3% of the population and are the most common reasons for valvular surgery because no drug-based treatments exist. Inheritable genetic mutations have now been established as the cause of mitral valve insufficiency, and four different missense mutations in the filamin A g...
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| Publié dans: | Biophys J |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6817519/ https://ncbi.nlm.nih.gov/pubmed/31542223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.08.032 |
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