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Metabolic constraints of swelling-activated glutamate release in astrocytes and their implication for ischemic tissue damage

Volume-regulated anion channel (VRAC) is a glutamate-permeable channel that is activated by physiological and pathological cell swelling and promotes ischemic brain damage. However, because VRAC opening requires cytosolic ATP, it is not clear if and how its activity is sustained in the metabolically...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Wilson, Corinne S., Bach, Martin D., Ashkavand, Zahra, Norman, Kenneth R., Martino, Nina, Adam, Alejandro P., Mongin, Alexander A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817373/
https://ncbi.nlm.nih.gov/pubmed/31032919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14711
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