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Hypoosmotic swelling modifies glutamate-glutamine cycle in the cerebral cortex and in astrocyte cultures

In our previous work, we found that perfusion of the rat cerebral cortex with hypoosmotic medium triggers massive release of the excitatory amino acid L-glutamate but decreases extracellular levels of L-glutamine (R.E. Haskew-Layton et al., PLoS ONE, 3: e3543). The release of glutamate was linked to...

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Detalhes bibliográficos
Main Authors: Hyzinski-García, María C., Vincent, Melanie Y., Haskew-Layton, Renée E., Dohare, Preeti, Keller, Richard W., Mongin, Alexander A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112305/
https://ncbi.nlm.nih.gov/pubmed/21517854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07289.x
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