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Two conventional PKC isoforms, α and βI, are involved in the ATP-induced regulation of VRAC and glutamate release in cultured astrocytes

Volume-regulated anion channels (VRACs) are activated by cell swelling and are permeable to inorganic and small organic anions, including the excitatory amino acids glutamate and aspartate. In astrocytes, ATP potently enhances VRAC activity and glutamate release via a P2Y receptor-dependent mechanis...

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Detalhes bibliográficos
Main Authors: Rudkouskaya, Alena, Chernoguz, Artur, Haskew-Layton, Renée E., Mongin, Alexander A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819458/
https://ncbi.nlm.nih.gov/pubmed/18315563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05312.x
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