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CDK4/6 inhibition in cancer: the cell cycle splicing connection

Cyclin-dependent kinase −4 and −6 (CDK4/6) inhibitors are currently being assessed in clinical trials for the treatment of many cancers including melanoma. While investigating the mechanisms of CDK4/6 inhibitor resistance in melanoma, we uncovered a mechanism of action of these inhibitors in regulat...

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Vydáno v:Mol Cell Oncol
Hlavní autoři: Sheppard, Karen E., AbuHammad, Shatha
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816418/
https://ncbi.nlm.nih.gov/pubmed/31692881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1673643
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