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CDK4/6 inhibition in cancer: beyond cell cycle arrest
Pharmacologic inhibitors of cyclin-dependent kinases 4 and 6 (CDK4/6) have recently entered the therapeutic armamentarium of clinical oncologists, and show promising activity in patients with breast and other cancers. Although their chief mechanism of action is inhibition of Retinoblastoma (RB) prot...
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| Publicado no: | Trends Cell Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6689321/ https://ncbi.nlm.nih.gov/pubmed/30061045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2018.07.002 |
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