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CDK4/6 Inhibition in Breast Cancer: Mechanisms of Response and Treatment Failure
PURPOSE OF REVIEW: To describe the role of D-type cyclins and CDKs 4 and 6 in breast cancer, and to discuss potential biomarkers for sensitivity or resistance to CDK4/6 inhibitors. RECENT FINDINGS: A small number of preclinical and clinical studies have explored potential mechanisms of CDK4/6 inhibi...
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| Publicado no: | Curr Breast Cancer Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5414585/ https://ncbi.nlm.nih.gov/pubmed/28479958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12609-017-0232-0 |
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