Matrine Exerts Hepatotoxic Effects via the ROS-Dependent Mitochondrial Apoptosis Pathway and Inhibition of Nrf2-Mediated Antioxidant Response

Matrine, an alkaloid isolated from Sophora flavescens, possesses a wide range of pharmacological properties. However, the use of matrine in clinical practice is limited due to its toxic effects. The present study investigated the roles of mitochondria and reactive oxygen species (ROS) in matrine-ind...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oxid Med Cell Longev
Main Authors: You, Longtai, Yang, Chunjing, Du, Yuanyuan, Liu, Yi, Chen, Gongsen, Sai, Na, Dong, Xiaoxv, Yin, Xingbin, Ni, Jian
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815593/
https://ncbi.nlm.nih.gov/pubmed/31737162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1045345
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker