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Molecular Mechanisms of Apoptosis in HepaRG Cell Line Induced by Polyphyllin VI via the Fas Death Pathway and Mitochondrial-Dependent Pathway

Polyphyllin VI, which is an active saponin, is mainly isolated from traditional medicinal plant Paris polyphylla, which causes liver damage in rats. In the present study, we aimed to explore the potential cytotoxicity of polyphyllin VI on the growth of HepaRG cells and to determine the molecular mec...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Toxins (Basel)
Asıl Yazarlar: Liu, Yi, Dong, Xiaoxv, Wang, Wenping, You, Longtai, Yin, Xingbin, Yang, Chunjing, Sai, Na, Leng, Xin, Ni, Jian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983257/
https://ncbi.nlm.nih.gov/pubmed/29762502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10050201
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